Web13 apr. 2024 · The initial mission of cancer genomics was to identify all cancer driver genes, primarily with the aid of next-generation sequencing (NGS)-based technologies. Cancer genomics studies have evolved from investigations of a handful of genes or tumors to large-scale, whole-genome, multi-omics and pan-cancer analyses ( Figure 1 B), as exemplified … http://www.bioon.com.cn/sub/showarticle.asp?sub_id=0&newsid=98245
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Web30 nov. 2024 · Acute or chronic cellular stress resulting from aberrant metabolic and biochemical processes may trigger a pervasive non-apoptotic form of cell death, generally known as ferroptosis. Ferroptosis is unique among the different cell death modalities, as it has been mostly linked to pathophysiological conditions and because several metabolic … Web20 mrt. 2024 · Here, we screened a panel of inhibitors of serine hydrolases—an enzyme class important for regulating lipid metabolism—for potentiation of ferroptosis in HT1080 fibrosarcoma cells. We found that DO264, a selective inhibitor of the lyso- and ox-phosphatidylserine (PS) lipase ABHD12, enhances ferroptotic death caused by RSL3, an … the sac shoes
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Web1 feb. 2024 · Jiashuo Zheng, M. Conrad Biology Cell metabolism 2024 230 PDF Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State. L. Magtanong, P. Ko, +9 authors S. Dixon Biology Cell chemical biology 2024 279 PDF Apatinib induced ferroptosis by lipid peroxidation in gastric cancer Li-ying Zhao, Yanmei … WebNitroxides were recently shown to catalyze the cross-dismutation of alkylperoxyl and hydroperoxyl radicals, making them uniquely effective radical-trapping antioxidants … Web19 apr. 2024 · Dear Sir, Coronavirus disease 2024 (COVID-19) has been declared a pandemic in 2024 [].Preliminary data suggests that obesity may aggravate the severity of respiratory diseases and of COVID-19 [].Patients with metabolic associated fatty liver disease (MAFLD) [], formerly known as non-alcoholic fatty liver disease, are often obese … the sac singapore