WebSecretory diarrhea is characterized by an osmolar gap <50 mOsm, Na >90 nM/L, and pH >5.6. However, this pattern can also be seen in osmotic diarrhea due to sodium-containing laxatives. Osmotic diarrhea is characterized by an osmolar gap of >100 mOsm, stool sodium of <60 meq/L and pH <5.3. WebOsmotic Gap: Osmotic gap is calculated as 290 mOsm/kg- (2 [Na]+2 [K]). Typically, stool osmolality is similar that seen in serum since the gastrointestinal (GI) tract does not secrete water. (1) An osmotic gap above 50 mOsm/kg is suggestive of an osmotic component contributing to the symptoms of diarrhea. (1,5,7)
Stool Osmotic Gap Calculator
WebMay 1, 2024 · For all cases, stool electrolytes and osmotic gap proved valuable in chronic diarrhea work-up. The imprecision of the assays ranged from 0% to 5.9%. ... (<10% by volume) into processed stool specimens to create (n = 4) high electrolyte concentration specimens. The concentrations of analytes in these samples were as following: Na + 368 … WebThe interpretation of the stool gap is as follows: low osmolar gap – values below 50 mOsm/kg – indicates secretory diarrhea; normal osmolar gap – values between 50 and … phones that do not need internet
Evaluation of Diarrhea - University of Louisville
WebFormed stool. Specimens in media or preservatives. Remarks Stability Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month Reference Interval 0-16 years: 271-296 mOsm/kg 17 years and older: 280-303 mOsm/kg Interpretive Data Compliance Category Standard Note Hotline History N/A CPT Codes 84999 Are you an ARUP Client? WebIn particular, several stools from lactu- lose-induced diarrhea had a much higher osmolality by vapor pressure than by freezing point osmometry. FECAL OSMOTIC GAP AND pH 547 None of the specimens had an osmolality <290 mOsm/kg by either method. WebJun 1, 2012 · Excess stool water then causes decreased stool consistency. Thus, diarrhea is a condition of altered intestinal water and electrolyte transport. The pathophysiologic mechanisms of diarrhea include osmotic, secretory, inflammatory, and altered motility. how do you start a meeting