WebAug 31, 2024 · Dihydrotanshinone I (DHT) is a natural component in Salvia miltiorrhiza and has been widely researched for its multiple bioactivities. However, poor solubility and biocompatibility of DHT limit its desirable application for clinical purposes. Herein, DHT was encapsulated with bovine serum albumin (BSA) to enhance bioavailability. Compared to … WebFor use with the X500R QTOF system powered by SCIEX OS
Did you know?
WebJul 31, 2015 · Cryptanshinone and dihydrotanshinone exhibit antibacterial activity against a broad range of Gram-positive bacteria, however, Tan IIA and Tan I are not toxic to bacteria [7,8]. Tanshinones are generally composed of four rings, including naphthalene or tetrahydronaphthalene ring A and B , an ortho -quinone ring C , and furan or … WebAug 29, 2024 · Dihydrotanshinone I (DHTS), extracted from Salvia miltiorrhiza, was found to be the most effective compound of tanshen extracts against cancer cells in our …
WebMay 1, 2024 · Dihydrotanshinone I (DIH), as a natural compound from the root of Salvia miltiorrhiza, has presented in vitro and in vivo therapeutic effects on different cancers such as liver cancer, breast ... WebSep 1, 2012 · Using the in vivo maximum plasma concentration (Cmax) of dihydrotanshinone I (11.29 ng/mL, 0.04 μM), the the change of AUC ranged from 0.14 to 1.42 % when the contribution of UGT1A7 towards the ...
WebActivation of P2X7 signaling, due to high glucose levels, leads to blood retinal barrier (BRB) breakdown, which is a hallmark of diabetic retinopathy (DR). Furthermore, several studies report that high glucose (HG) conditions and the related activation of the P2X7 receptor (P2X7R) lead to the over-expression of pro-inflammatory markers. In order to identify … WebDihydrotanshinone (DHT), one of the major ingredients of Salvia miltiorrhiza Bunge (Danshen), displays many bioactivities. However, the activity and underlying mechanism …
WebSep 1, 2024 · Dihydrotanshinone I ameliorated high-fat induced cardiac hypertrophy. Cardiac hypertrophy was assessed at the end of the study by using histological analysis and qPCR. (A) Representative ...
WebDec 14, 2024 · Dihydrotanshinone I (DHT) is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. However, its role in atherosclerosis ... guitar hero play nowWebApr 13, 2024 · Consistently, in vitro protein assay showed that Sm2OGD3 catalyzed the conversion of cyptotanshinone, 15,16-dihydrotanshinone I and 1,2,15,16-tetrahydrotanshinone I into tanshinone IIA, tanshinone I and 1,2-dihydrotanshinone I, respectively. Thus, Sm2OGD3 functions as tanshinone 15,16-dehydrogenase and is a … guitar hero playstation 3 bundleWebDihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function.[9] Dihydrotanshinone I induces caspase and ROS dependent apoptosis and autophagy, mediated by mitochondria in colon cancer; it could be a promising leading compound for the development of anti-tumor agent or be developed as an ... guitar hero price checkWebDihydrotanshinone treatment leads to nuclear condensation in SHG-44 cells. To further confirm the pro-apoptosis role of dihydrotanshinone in SHG-44 cells, Hoechst 33258 staining was applied to examine the nucleus morphology. After the staining, a blue fluorescent signal in normal cells is usually weak and evenly colored, while in apoptotic ... guitar hero platformsWebJan 18, 2008 · The coefficients of variation and the relative errors of tanshinone I, dihydrotanshinone I, tanshinone IIA and cryptotanshinone for intra- and inter-assay at four quality control (QC) concentrations were 1.1–5.1% and −4.0–6.0%, respectively. The lower limit of quantification for tanshinone I, dihydrotanshinone I, tanshinone IIA and ... bow and melcWebDihydrotanshinone C18H14O3 CID 5316743 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... guitar hero phoneWebSep 28, 2024 · Planta Med. 2002 Dec;68(12):1077-81. Dihydroisotanshinone I protects against menadione-induced toxicity in a primary culture of rat hepatocytes.[Pubmed: 12494333] Dihydroisotanshinone I is a phenanthrenequinone derivative isolated from the roots of Salvia trijuga Diels. METHODS AND RESULTS: The present study … bow and meow pet spa chicago