WebSep 15, 2008 · c-Mpl contains 2 YXXΦ motifs in its cytoplasmic domain at Tyr8 (Y 8 RRL; numbering is from the first cytoplasmic domain residue) and Tyr78 (Y 78 RRL). Previous findings suggest that Y 78 acts as a negative regulator in a truncated (T-83) form of c-Mpl, 33 although the function of this residue in a full-length receptor remains unclear. A role … Webcytoplasmic granule 細胞(質)顆粒{さいぼう(しつ)かりゅう} cytoplasmic heredity cytoplasmic heredity細胞質遺伝さいぼうしついでん; cytoplasmic hybrid 細胞質雑種{ …
cytoplasmic domain 意味 - cytoplasmic domain 日本語の意味
WebMar 1, 2024 · FcγRIIB, the only inhibitory IgG Fc receptor, functions to suppress the hyper-activation of immune cells. Numerous studies have illustrated its inhibitory function through the ITIM motif in the cytoplasmic tail of FcγRIIB. However, later studies revealed that in addition to the ITIM, the transmembrane (TM) domain of FcγRIIB is also indispensable … WebSep 19, 2003 · Bidirectional integrin signaling is accomplished by coupling extracellular conformational changes to an unclasping and separation of the α and β cytoplasmic domains, a distinctive mechanism for transmitting information across the plasma membrane. Although critical for development, immunity, wound healing, and metastasis, … ugarte facebook
定義 CD: 細胞質ドメイン - Cytoplasmic Domain
WebDec 1, 2008 · IL-2 and IL-15 share the same Jak1/Jak3 and Stat3/Stat5 signal transduction pathway mediated via the IL-2Rβ/γ c complex. 17,29 IL-2Rα binds IL-2 with low affinity but has a very short 13–amino acid cytoplasmic domain 30 and cannot transduce a signal. Because of its rapid on-rate for IL-2, IL-2Rα is believed to “recruit” IL-2 to the cell surface … WebSep 14, 2024 · LRRC8 channels share a modular organization consisting of a membrane-inserted pore domain and cytoplasmic leucine-rich repeat (LRR) domains 18. In the pore domain, the ion conduction path running ... WebDec 6, 2015 · In addition, a cytoplasmic domain–specific mAb can be used for analysis of PD-L1 expression even in the presence of a PD-L1 therapeutic mAb. We immunized PD-L1–deficient mice with a PD-L1 cytoplasmic domain peptide and generated an mAb, 9A11, that recognizes the human PD-L1 cytoplasmic domain. Initial screening of the antibody … uga rushing leaders